lithium 3-methyl-2-[[[methyl-[(2-propan-2-yl-4-thiazolyl)methyl]amino]-oxomethyl]amino]butanoate - Names and Identifiers
lithium 3-methyl-2-[[[methyl-[(2-propan-2-yl-4-thiazolyl)methyl]amino]-oxomethyl]amino]butanoate - Physico-chemical Properties
lithium 3-methyl-2-[[[methyl-[(2-propan-2-yl-4-thiazolyl)methyl]amino]-oxomethyl]amino]butanoate - Introduction
N-[N-Methyl-N-((2-isopropyl-4-thiazolyl)methyl)aminocarbonyl]-L-valine salt (MTX for short) is a chemical substance whose Properties, Uses, preparation methods and safety information are as follows:
Nature:
- MTX is a white crystalline powder with a special amino acid structure.
-It has good solubility and is soluble in water and some organic solvents.
- MTX is stable in an acidic environment, but is easily decomposed by hydrolysis under alkaline conditions.
Use:
- MTX is an anti-metabolic drug, which is widely used in clinical treatment, especially in the treatment of anti-tumor and rheumatoid arthritis.
-It plays a therapeutic role by inhibiting the synthesis of DNA and RNA, interfering with cell proliferation and inflammatory response.
Method:
The preparation method of-MTX is more complicated. One of the common methods is to obtain MTX by reacting valine with methanesulfonyl chloride (MsCl).
Safety Information:
- MTX is a toxic chemical and should be used and handled in accordance with safe procedures.
-When using MTX, pay attention to personal protection and avoid contact with skin, eyes and mucous membranes.
-MTX consumption or inhalation may cause health hazards, so the dosage should be strictly controlled and follow medical advice.
-Pregnant and lactating women should avoid exposure to MTX because it may have harmful effects on embryos and babies.
-When using or disposing of MTX, please follow appropriate waste disposal procedures to prevent environmental pollution.
Last Update:2024-04-09 20:49:11